Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels
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the role of application of dynamic assessment approach in improvement of iranian efl writing performance at different language proficiency levels
the present study sought to investigate the role of dynamic assessment (da) in improvement of iranian efl writing performance at different language proficiency levels. to this end, after conducting the quick placement test, 60 iranian efl learners were assigned to two groups with different language proficiency levels. in both groups each participant wrote two compositions, one before and one af...
Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QTc interval in healthy subjects
AIMS Exenatide has been demonstrated to improve glycaemic control in patients with type 2 diabetes, with no effect on heart rate corrected QT (QTc ) at therapeutic concentrations. This randomized, placebo- and positive-controlled, crossover, thorough QT study evaluated the effects of therapeutic and supratherapeutic exenatide concentrations on QTc . METHODS Intravenous infusion was employed t...
متن کاملHospital acquired Acute Kidney Injury is associated with increased mortality but not increased readmission rates in a UK acute hospital
BACKGROUND Acute Kidney Injury (AKI) has evoked much interest over the past decade and is reported to be associated with high inpatient mortality. Preventable death and increased readmission rates related to AKI have been the focus of considerable interest. METHODS We studied hospital acquired AKI in all emergency hospital admissions, except transfers from ICU to ICU or patients known to rena...
متن کاملAbortive potency of Chlamydophila abortus in pregnant mice is not directly correlated with placental and fetal colonization levels.
Abortion, placental and fetal colonization, and levels of gamma interferon were analyzed for four Chlamydophila abortus strains presenting antigenic variations in a mouse model. Expression of virulence of these strains varied and indicated that abortion was not directly related to the number of bacteria in the placenta, and thus, other factors may have an important role in activating the aborti...
متن کاملNeonatal and Fetal Outcomes of Pregnant Mothers with Hypertensive Disorder of Pregnancy at Hospitals in Wolaita Zone, Southern Ethiopia
Background & aim: Hypertensive disorders of pregnancy are among the severe medical disorders peculiar to pregnancy. It is one of the risk factors during pregnancy either for the mother or fetus or both. Therefore, this study aimed to assess fetal and neonatal outcomes of mothers with hypertensive disorders of Pregnancy. Methods: This hospital-based cross-sectional study was conducted on neonate...
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ژورنال
عنوان ژورنال: EBioMedicine
سال: 2021
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2020.103167